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P1116 HiPure Plasmid EF Mega Kit

The HiPure Plasmid DNA Mega Kits combine the power of HiPure technology with the time-tested consistency of alkaline-SDS lysis of bacterial cells to deliver high-quality DNA.

Immune Protective Evaluation Elicited by DNA Vaccination With Neospora caninum Dense Granules Proteins in Mice
P1231 HiPure Plasmid EF Midi Kit

Isolation up to 500µg endotoxin-free plasmid DNA from 25-50ml bacterial culture

【Cell Reports】Template-independent genome editing in the Pcdh15av−3j mouse, a model of human DFNB23 nonsyndromic deafness

【Cell Reports】Template-independent genome editing in the Pcdh15av−3j mouse, a model of human DFNB23 nonsyndromic deafness
P1811 MagPure Plasmid Mini Kit

Isolation up to 10µg plasmid DNA from 1.5ml bacterial culture

【Nature Catalysis】Efficient exploration of terpenoid biosynthetic gene clusters in filamentous fungi
R4011 HiPure Total RNA Kit

The Kit provides fast purification of high-quality RNA from cells, tissues, and yeast using silica-membrane spin columns with a binding capacity of 100ug RNA.

【signal transduction and targeted therapy】Blockade of NMT1 enzymatic activity inhibits N-myristoylation of VILIP3 protein and suppresses liver cancer progression

【Signal Transduction and Targeted Therapy】SARS-CoV-2 hijacks cellular kinase CDK2 to promote viral RNA synthesis

【CELL】Visualizing Intracellular Organelle and Cytoskeletal Interactions at Nanoscale Resolution on Millisecond Timescales

【Journal of Extracellular Vesicles】Extracellular vesicles from lung tissue drive bone marrow neutrophil recruitment in inflammation

【Cell Metabolism】Triose Kinase Controls the Lipogenic Potential of Fructose and Dietary Tolerance

【Nature Communications】TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection

【Nature Communications】Structures of a deltacoronavirus spike protein bound to porcine and human receptors

【Nature Communications】Structures of a deltacoronavirus spike protein bound to porcine and human receptors

【CHEMICAL ENGINEERING JOURNAL】One-step preparation of the engineered titanium implant by rationally designed linear fusion peptides with spacer-dependent antimicrobial, anti-inflammatory and osteogenic activities

【Science Advances】R-loops coordinate with SOX2 in regulating reprogramming to pluripotency

【BIOMATERIALS】Untangling the response of bone tumor cells and bone forming cells to matrix stiffness and adhesion ligand density by means of hydrogels

【BIOMATERIALS】Molecular recognition-directed site-specific release of stem cell differentiation inducers for enhanced joint repair
R4111 HiPure Total RNA Plus Kit

This provides fast purification of high-quality RNA from cells, tissues, and yeast using silica-membrane spin columns with a binding capacity of 100μg RNA.

【Bioactive Materials】Spontaneous immunomodulation and regulation of angiogenesis and osteogenesis by Sr/Cu-borosilicate glass (BSG) bone cement to repair critical bone defects

【Cell Host & Microbe】Integrative Analysis of Zika Virus Genome RNA Structure Reveals Critical Determinants of Viral Infectivity

【Nature Communications】PCGF6 controls neuroectoderm specification of human pluripotent stem cells by activating SOX2 expression

【NUCLEIC ACIDS RESEARCH】Active endogenous retroviral elements in human pluripotent stem cells play a role in regulating host gene expression

【Nature Communications】Gain-of-function genetic screening identifies the antiviral function of TMEM120A via STING activation

【JOURNAL OF CLINICAL INVESTIGATION】An Asia-specific variant of human IgG1 represses colorectal tumorigenesis by shaping the tumor microenvironment

【Bioactive Materials】Dimethylamino group modified polydopamine nanoparticles with positive charges to scavenge cell-free DNA for rheumatoid arthritis therapy

【Small】Electrospun PCL/MoS2 Nanofiber Membranes Combined with NIR-Triggered Photothermal Therapy to Accelerate Bone Regeneration

【PNAS】A multiomic study uncovers a bZIP23-PER1A–mediated detoxification pathway to enhance seed vigor in rice

【BIOMATERIALS】Implantable and degradable antioxidant poly(ε-caprolactone)-lignin nanofiber membrane for effective osteoarthritis treatment

【NUCLEIC ACIDS RESEARCH】Phosphorylation of Msx1 promotes cell proliferation through the Fgf9/18-MAPK signaling pathway during embryonic limb development

【Clinical and Translational Medicine】Genome-wide gain-of-function screening identifies EZH2 mediating resistance to PI3Kα inhibitors in oesophageal squamous cell carcinoma

【PNAS】Orthogonal genome-wide screens of bat cells identify MTHFD1 as a target of broad antiviral therapy

【JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH】The circular RNA circZFR phosphorylates Rb promoting cervical cancer progression by regulating the SSBP1/CDK2/cyclin E1 complex
R4130 Hipure Universal RNA Kit

The HiPure Universal RNA Kit integrates phenol/guanidine-based sample lysis and silica membrane purification of total RNA. MagZol reagent, included in the kits, is a monophasic solution of phenoland guanidine thiocyanate, designed to facilitate lysis of fatty tissues and inhibit RNase.

【Journal of Advanced Research】Targeting ARF1-IQGAP1 interaction to suppress colorectal cancer metastasis and vemurafenib resistance

【ACS Nano】Tailoring Chemoimmunostimulant Bioscaffolds for Inhibiting Tumor Growth and Metastasis after Incomplete Microwave Ablation

【Science Advances】α-Ketoglutaric acid ameliorates hyperglycemia in diabetes by inhibiting hepatic gluconeogenesis via serpina1e signaling

【Nature Communications】FUT8-mediated aberrant N-glycosylation of B7H3 suppresses the immune response in triple-negative breast cancer

【CHEMICAL ENGINEERING JOURNAL】Electro-fermentation enhances H2 and ethanol co-production by regulating electron transfer and substrate transmembrane transport

【Theranostics】Human umbilical cord-derived mesenchymal stem cell therapy ameliorates lupus through increasing CD4+ T cell senescence via MiR-199a-5p/Sirt1/p53 axis

【PNAS】An L1 retrotransposon insertion–induced deafness mouse model for studying the development and function of the cochlear stria vascularis

【Autophagy】MAPK1/3 kinase-dependent ULK1 degradation attenuates mitophagy and promotes breast cancer bone metastasis

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