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Lancet: the risk of severe illness and death is greatly increased due to the co-infection of SARS-CoV-2 and influenza viruses

Release date:2022.03.31

SARS-CoV-2

co-infection with influenza viruses, respiratory syncytial virus, or adenoviruses


Published: March 25, 2022  DOI: https://doi.org/10.1016/S0140-6736(22)00383-X

The team's study of more than 300 thousand new inpatients found that the risk of serious illness and death in adults co-infected with sars-cov-2 and influenza viruses increased significantly compared to those only infected with COVID-19. Specifically, the risk of requiring ventilator treatment is 4.14 times and the risk of death is 2.35 times.

Tests for respiratory viral co-infections were recorded for 6965 patients with SARS-CoV-2. Viral co-infection was detected in 583 (8·4%) patients: 227 patients had influenza viruses, 220 patients had respiratory syncytial virus, and 136 patients had adenoviruses. Co-infection with influenaza viruses was associated with increased odds of receiving invasive mechanical ventilation compared with SARS-CoV-2 monoinfection (table). SARS-CoV-2 co-infections with influenza viruses and adenoviruses were each significantly associated with increased odds of death.

The authors said that C0-infection with coronavirus and influenza virus is not common, but it is important to recognize that this situation is actually happening, and once it happens, it will greatly increase the risk of severe illness and death. The treatment of COVID-19 infection and influenza virus infection is not the same, so it is necessary to detect influenza at the same time. At the same time, the study also stressed the importance of vaccination against coronavirus and influenza.

For details, please visit https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00383-X/fulltext


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